demineral corticocancellous powder

Company Profile & Quality Assurance: TRC (Kish Tissue Regeneration Corp) is a knowledge-based enterprise specializing in the production of bio-implants. The company’s bone product group is designed to facilitate bone regeneration. TRC is comprised of specialized professionals committed to maintaining the highest standards, complying with FDA regulations for human-origin therapeutic products.

Product Overview & Mechanism of Action: In the production of demineralized products, inorganic minerals that may inhibit osteoinduction are removed from the collagen matrix. This process exposes the Bone Morphogenetic Proteins (BMPs), thereby enhancing osteoinductive properties and accelerating the remodeling process. Demineralized bone powders demonstrate faster resorption compared to mineralized options and offer higher bioavailability of BMPs. Consequently, the rates of induction and fusion are significantly elevated in this form.

Processing: This product is produced via freeze-drying and sterilized using gamma irradiation. Note: Due to the demineralization process, the BMP concentration per volume is significantly higher than that of mineralized equivalents.

Particle Sizes & Indications: This product is available in specific particle sizes tailored for different clinical applications:

• 150 – 1000 microns: Recommended for use around implants and filling fenestrations/pores.

• 150 – 2000 microns: Recommended for filling micro-gaps surrounding bone block strips.

Preparation: It is strictly recommended to rehydrate the product using a physiological solution prior to implantation.